[Hiring] Senior Director, Global Supply Chain Network Planning & Risk Management @Syndax Pharmaceuticals

Role Description

Syndax Pharmaceuticals is looking for a Senior Director, Global Supply Chain Network Planning & Risk Management. Reporting to the Senior Vice President, Pharmaceutical Development and Manufacturing, this role will lead integrated supply planning, network strategy, inventory management, and supply risk management across Syndax’s clinical and commercial supply chains.

• Align demand forecasts, manufacturing plans, inventory strategies, production activities, and network capabilities with business objectives and patient needs.
• Partner closely with External Manufacturing, Clinical Supply Chain, Logistics, CMC, Quality, Regulatory, Commercial, Finance, and Clinical Operations to ensure supply reliability and execution against the supply plan.

Key Responsibilities

• Lead integrated Sales and Operations Planning (S&OP) aligning demand, manufacturing capacity, inventory, financial plans, and business priorities.
• Own global supply planning across clinical and commercial programs for drug substance and drug product.
• Establish demand-planning processes that integrate clinical enrollment forecasts and finished goods requirements.
• Lead demand and supply balancing across the network, identifying constraints and decisions required to protect patient supply.
• Develop long-range network and capacity strategies supporting portfolio growth and supply resilience.
• Establish inventory and safety-stock strategies that balance service, supply risk, expiry exposure, cost, and working capital.
• Monitor inventory health, planning accuracy, capacity, and supply performance and drive timely corrective actions.
• Develop and maintain a robust supply risk management program covering internal and external risk surveillance.
• Maintain an integrated supply risk register and provide clear visibility to emerging risks and potential impacts.
• Lead scenario planning and business-continuity strategies addressing network vulnerabilities.
• Partner with various functions to chair a weekly Production Control meeting to confirm alignment and execution of production activities.
• Escalate production, release, inventory, or material-flow constraints promptly and track commitments through resolution.
• Lead supply planning for product launches, new markets, and lifecycle changes.
• Lead development and implementation of planning processes, systems, analytics, and performance measures.
• Communicate supply outlook, production performance, risks, and required decisions clearly to senior leadership.
• Build and develop a high-performing global supply chain network planning and risk management team.
• Travel domestically and internationally as required.

Qualifications

• Bachelor’s degree in supply chain, engineering, business, operations, pharmaceutical sciences, chemistry, or a related discipline required; MBA or advanced degree preferred.
• 15+ years of progressive pharmaceutical or biotechnology supply-chain experience.
• Deep expertise in supply planning, demand planning, S&OP, C&OP, inventory management, and network planning.
• Demonstrated experience building and operating structured supply risk management programs.
• Experience leading cross-functional production control or supply execution forums.
• Experience supporting clinical and commercial products within highly outsourced global supply chains.
• Experience with small molecule active pharmaceutical ingredient and oral solid dose supply chains required; biologics experience preferred.
• Demonstrated success supporting commercial launches, market expansion, and lifecycle management.
• Experience working with global manufacturing networks and international contract development and manufacturing organizations.
• Demonstrated success designing and implementing planning processes and performance-management systems.
• Experience selecting, implementing, or improving enterprise resource planning and supply-chain planning systems.
• Lean Six Sigma Green Belt or Black Belt certification preferred.
• Strong analytical, financial, strategic-planning, facilitation, and structured problem-solving capabilities.
• Excellent leadership, communication, executive presence, and cross-functional influence.
• Strategic and pragmatic leader who drives execution and builds sustainable planning and risk-management capabilities.

Location

Syndax’s corporate office is in New York, NY.

Benefits

• Total compensation and rewards package that is among the most competitive in the industry.
• Base pay determined within a range based on market data, experience, qualifications, and internal equity.
• Equity offering, annual target bonuses, and an outstanding benefits program.
• Anticipated annualized salary range for this role is $270,000 - $290,000.

Company Description

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company’s pipeline include:

• A menin inhibitor for R/R acute leukemia.
• A monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease.

For more information, please visit www.syndax.com or follow the Company on X and LinkedIn.

Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.