[Hiring] Executive Director, Clinical Supply Management @Jade Biosciences

Role Description

Jade is developing potentially transformational, disease-modifying therapies for people living with autoimmune diseases. With three biologics programs in the clinic and multiple ongoing studies from Phase I to Phase III, we are seeking an experienced Executive Director, Clinical Supply Management to join our CMC leadership team and make sure every patient in our trials receives the right investigational product, on time.

Reporting to the Chief Technology Officer (Head of CMC), you will own clinical supply strategy, planning and execution for all Jade programs. You will shape and scale the Clinical Supply Management function, growing and mentoring a team of internal employees and contractors, and you will lead a global network of CMOs and logistics partners supporting complex, multi-country and multi-site studies with ambitious timelines and enrollment targets.

This is a high-impact role for a self-starter who combines strategic thinking with hands-on execution. You will work closely with Clinical Operations and Clinical Development to secure supply for every planned study, help prepare the supply chain for BLA filing, launch and commercial readiness, and contribute directly to Jade’s key corporate goals.

Key Responsibilities

• Provide strategic and operational leadership for Jade’s Clinical Supply Management function.
• Further develop and scale the team through a combination of internal headcount and external partners, including recruiting, onboarding and mentoring team members and consultants.
• Develop robust business processes and SOP in close collaboration with the Quality function.
• Develop and implement the clinical supply strategy for all Jade programs, from early-stage (Phase 1/2) through late-stage (Phase 3) development.
• Build and maintain integrated global demand forecasts and supply plans based on protocols, enrollment projections and site activation plans.
• Advise on potential risk and challenges to Senior Management and peer groups such as Clinical Operations and Development.
• Partner closely with Clinical Operations and Clinical Development on study-specific supply strategies.
• Select, contract and manage clinical supply CMOs, depots, couriers, logistics providers, and other critical suppliers.
• Direct labeling, packaging, blinding, cold-chain storage and global distribution for all drug product formats.
• Define supply requirements for IRT/IxRS systems, including resupply strategies and user acceptance testing.
• Maintain full compliance with Jade SOPs, cGMP, GDP, GCP, ICH guidelines and applicable global regulatory and import/export requirements.
• Manage the clinical supply budget, and report regularly and concisely to stakeholders and senior management on inventory, supply and demand, changes and risks across all programs.

Qualifications

• Bachelor’s or Master’s degree (or equivalent) in Life Sciences, Chemical Engineering or a related field.
• 15+ years of progressive experience in clinical supply chain management, ideally with biologics, including significant experience leading teams.
• Proven experience managing clinical supply for biologics in vials within cold-chain environments.
• Experience supporting multiple early- and late-stage programs, including multi-country Phase 3 studies.
• Comprehensive understanding of global regulatory and import/export requirements across Europe, North America, China, Japan and Rest of World (ROW).
• Hands-on experience with IRT/IxRS systems, clinical supply forecasting tools and budget management.
• Demonstrated success building and scaling clinical supply functions.
• Exceptional communication, leadership and interpersonal skills.
• A strategic thinker with a proven execution record, strong problem-solving skills.

Requirements

• Experience with pre-filled syringes and combination products such as autoinjectors highly preferred.

Benefits

• This is a remote role; periodic travel to team and company events is required.
• The anticipated salary range for candidates for this role is $280,000 - $300,000.
• The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.

Company Description

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases.