[Hiring] Principal Product Manager @Twin Health

Role Description

We’re looking for a Principal Product Manager to help define and build the core intelligence system at the heart of Twin. This role sits at the intersection of:

• LLMs and agent systems
• Human + AI orchestration
• Real-time health guidance
• Voice and conversational interfaces
• Platform and developer ecosystems

You will:

• Define how the Digital Twin behaves across text, voice, and proactive experiences
• Build specialized sub-agents that plug into the core Digital Twin
• Create the platform and primitives that enable teams across Twin to build agents safely and quickly
• Push the boundaries of what’s possible with modern AI systems in healthcare

Responsibilities

• Define the Digital Twin intelligence system
• Translate the core loop—Sense → Understand → Decide → Act → Learn—into a scalable agent system
• Define how the Digital Twin reasons, responds, escalates, and coordinates across experiences
• Shape the future of AI-driven health guidance across text, voice, and proactive interactions
• Build specialized agent systems including:
  • Sensor intelligence
  • Scheduling and coordination
  • Nutrition
  • Exercise, sleep, and stress
  • Insights
  • App help and operational support
  • Care-team interaction orchestration
• Build the platform that enables the company
• Create the foundations that allow PMs and teams to build on top of the Digital Twin
• Establish primitives for:
  • Agent creation and orchestration
  • Memory and personalization
  • Evaluation and monitoring
• Define next-generation conversational experiences
• Build deeply personalized experiences across chat, two-way voice, and ambient guidance
• Define conversation patterns and interaction models that feel natural, trusted, and useful
• Operate at frontier speed
• Rapidly move from insight → prototype → experiment → production
• Partner deeply with AI Engineering, Design, Clinical, and Product teams
• Continuously evaluate emerging capabilities across LLMs, speech, memory, and agent systems
• Establish metrics and evaluation systems for:
  • Guidance quality
  • Conversation effectiveness
  • Problem resolution
  • Behavior change
• Other duties as assigned.

Qualifications

• 8+ years in Product Management (or equivalent impact), including significant experience building AI-native products
• 3+ years building and shipping products powered by:
  • LLMs
  • Agents
  • RAG
  • Personalization systems
• Track record of owning complex, system-level products
• Experience shipping conversational or voice experiences with measurable impact
• Strong product judgment and analytical instincts:
  • Experimentation
  • Evaluation design
  • KPI definition
• Builder mindset—you move from concept to shipped system quickly

Benefits

• A competitive compensation package in line with leading technology companies
• A remote and accomplished global team
• Opportunity for equity participation
• Unlimited vacation with manager approval
• 16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents
• 100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options
• 401k retirement savings plan