[Hiring] Senior Clinical Trial Manager @Syneos Health

Role Description

The Sr. Clinical Trial Manager (Clinical Research Medical Advisor) is responsible for providing medical and scientific leadership to ensure the high-quality execution of clinical trials and studies in the assigned country or cluster. This role bridges Clinical Development and cross-functional teams, ensuring local medical input and compliance with regulatory standards.

Key Responsibilities

• Lead local clinical/medical aspects of trial implementation, including protocol review, site selection support, feasibility assessments, and recruitment strategy planning.
• Act as the medical representative to support study design, regulatory interactions, and site training to ensure protocol adherence and patient safety.
• Identify proactively recruitment challenges or operational challenges and develop migration plans.
• Provide protocol/compound and indication trainings to internal and external partners.
• Provide medical input for Informed Consent Forms (ICFs) and safety reporting.
• Partner with clinical operations, regulatory, medical affairs, and external experts to optimize trial execution.
• Support safety oversight: review serious adverse events (SAEs), provide pharmacovigilance support, and ensure clinical data quality.
• Contribute to early trial start-up by validating study feasibility and supporting site engagement and training.
• Ensure adherence to Good Clinical Practice (GCP), ICH guidelines, and country regulations.
• Contribute to internal and external scientific discussions, including advisory boards and investigator meetings.
• Provide clinical/medical expertise for regulatory inspections, audits, and trial documentation.
• May work cross country.

Qualifications

• Advanced scientific degree: M.D., Ph.D., or Pharm.D. (M.D. preferred); subspecialty training desirable.
• Local Language fluency required.
• Fluent in English (speaking and writing).
• Minimum 3 years in clinical development or clinical practice in the pharmaceutical or healthcare sector.
• Strong understanding of clinical trial design, implementation, and ICH/GCP principles.
• Proven ability to analyze complex clinical/scientific issues and provide practical solutions.
• Strong communication and leadership skills to work cross-functionally.
• Problem-solving mindset and agility across therapeutic areas.
• Excellent presentation skills in English and local language.
• Strong protocol review and feasibility assessment skills.
• Understanding of safety and regulatory requirements in clinical trials.
• Experience supporting regulatory submissions, audits, and inspections.

Requirements

• Up to 50% travel.

Benefits

• Passionate about developing our people through career development and progression.
• Supportive and engaged line management.
• Technical and therapeutic area training.
• Peer recognition and total rewards program.
• Commitment to building an inclusive culture.
• Opportunity to shape solutions that impact lives.