Role Description
As the Microbiologist II, the candidates shall perform specified portions of scientific work involving studies of genomic sequencing of the samples, biological activities, and/or processes of viruses and their component parts.
Responsibilities
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Perform virus diagnostic and genomic sequencing, including qPCR assay, genomic sequencing using Illumina and ONT platforms.
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Perform research activities to improve, enhance or develop new assay developments with the incorporation of advanced technologies.
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Maintain cell lines, virus variants, and other reagents required for the performance of research activities, including APOBEC-related research.
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Maintain detailed laboratory records of activities including documentation fitting for submission of results for peer-reviewed publications.
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Participate in branch international research activities to evaluate laboratory capabilities, procure equipment and reagents for diagnostic assays, and train laboratory personnel in Monkeypox virus diagnostic assays.
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Assist with ordering reagents and maintenance of laboratory space for conducting research activities.
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Propagate and purify Monkeypox viruses and orthopoxviruses for use in assays for validation of diagnostic assays and investigative purposes.
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Perform nucleic acid extractions on animal samples known or potentially infected with zoonotic agents, including Monkeypox virus and orthopvirus species.
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Maintain and consolidate all records related to historical Monkeypox virus and orthopoxviruses, and investigate all reagents produced during these studies.
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Analyze data relevant to laboratory investigations as well as outbreak response efforts with skills and knowledge of bioinformatics.
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Effectively communicate research activities by presentations in lab, team, and branch meetings.
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Present works in national/international conferences and prepare manuscripts and research articles for publication.
Qualifications
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Working knowledge of molecular biology, virology, infectious disease diagnostics, and laboratory research methods.
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Experience performing nucleic acid extraction, qPCR testing, and routine molecular diagnostic procedures.
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Working knowledge of genomic sequencing methods, including Illumina and/or Oxford Nanopore Technologies (ONT) platforms.
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Experience with cell culture, maintenance of cell lines, virus stocks, laboratory reagents, and research materials.
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Basic to intermediate knowledge of bioinformatics and analysis of genomic sequencing data.
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Knowledge of laboratory biosafety, biosecurity, quality assurance, contamination control, and safe handling of infectious materials.
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Ability to follow established protocols, assist with assay development and validation, troubleshoot routine laboratory issues, and accurately document results.
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Strong laboratory recordkeeping, data management, and organizational skills, including maintenance of specimen, reagent, and research records.
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Ability to analyze laboratory data and contribute to technical reports, presentations, manuscripts, and research documentation.
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Effective communication and teamwork skills, including the ability to support training, laboratory coordination, and domestic or international research activities.
Requirements
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Bachelor's Degree in Biology, Microbiology or a related field.
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2-5 years of relevant experience.
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Ability to obtain and maintain CDC Public Trust Clearance.
Preferred Qualifications
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Masterβs degree in microbiology, molecular biology, virology, biotechnology, bioinformatics, or a related scientific field.
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Approximately 2β5 years of relevant laboratory experience in molecular diagnostics, infectious disease research, virology, or public health laboratory science.
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Hands-on experience performing qPCR assays and preparing samples or libraries for genomic sequencing.
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Experience using Illumina, ONT, or comparable next-generation sequencing technologies.
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Experience with cell culture, viral propagation, nucleic acid extraction, and maintenance of laboratory reagents or biological materials.
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Familiarity with Mpox virus, orthopoxviruses, zoonotic pathogens, or other infectious disease agents.
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Experience using basic or intermediate bioinformatics tools for sequence analysis, genome assembly, alignment, or variant identification.
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Experience assisting with assay development, validation, method improvement, or implementation of new laboratory technologies.
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Experience supporting infectious disease surveillance, outbreak response, or laboratory research activities.
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Experience contributing to scientific presentations, technical reports, manuscripts, training activities, or laboratory capacity-building efforts.
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Prior experience with CDC.
Benefits
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Competitive base salary commensurate with qualifications and experience.
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Comprehensive benefits package, including medical, dental, and vision insurance.
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401(k) plan with company matching.
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Tax-deferred savings options.
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Supplementary benefits.
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Paid time off.
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Professional development opportunities.