Role Description
As a Microbiologist III the candidate shall perform specified portions of scientific work involving studies of immune responses after vaccination, humoral and cellular immune responses, biological activities, and/or processes of viruses, humans, and animals, and their component parts.
Responsibilities
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Perform virus diagnostic testing, including DFA (Direct Fluorescent Antibody test), RFFIT (Rapid fluorescent focus inhibition test), and other assays for either confirmation or screening.
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Perform research activities to improve, enhance or develop new diagnostic assay developments with the incorporation of advanced technologies.
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Train other members of the laboratory or external laboratory researchers with diagnostic assays.
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Participate in branch international research activities to evaluate laboratory capabilities, procure equipment and reagents for diagnostic assays, and train laboratory personnel in virus diagnostic assays.
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Participate in and lead animal studies in which animals are inoculated with viruses.
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Lead and participate in studies performed in the BSL-2 and BSL-3 laboratories as they relate to immunology and protein-based diagnostics or as needed.
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Maintain detailed laboratory records of activities, including documentation fitting for submission of results for peer-reviewed publications.
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Maintain cell lines, virus variants, and other reagents required for the performance of research activities.
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Assist with ordering reagents and maintenance of laboratory space for conducting research activities.
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Propagate and purify viruses for use in assays for validation of diagnostic assays and investigative purposes.
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Perform nucleic acid extractions on animal samples known or potentially infected with zoonotic agents, including rabies virus and orthopoxvirus species.
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Maintain and consolidate all records as related to historical viruses, and investigation of all reagents produced during these studies.
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Analyze data relevant to laboratory investigations as well as outbreak response efforts.
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Effectively communicate research activities through presentations in lab, team, and branch meetings.
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Present works in national/international conferences and prepare manuscripts and research articles for publication.
Qualifications
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Working knowledge of virology, immunology, molecular biology, serology, and diagnostic microbiology applicable to viral diseases and vaccine-related immune responses.
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Hands-on experience performing viral diagnostic assays, including fluorescent antibody, neutralization, serologic, immunologic, or comparable confirmatory and screening methods.
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Experience supporting assay development, optimization, validation, and implementation of new diagnostic or immunologic technologies.
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Ability to conduct laboratory studies in BSL-2 and/or BSL-3 environments while following established biosafety, biosecurity, quality, and contamination-control procedures.
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Experience with cell culture, maintenance of cell lines and viral stocks, and propagation and purification of viruses for diagnostic or research purposes.
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Working knowledge of humoral and cellular immune response testing and laboratory methods used to evaluate vaccine or infection-related immune responses.
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Ability to support or participate in animal studies involving viral challenge or inoculation and to process associated specimens in accordance with established protocols.
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Strong laboratory documentation and records-management skills, including maintenance of protocols, study records, reagent inventories, experimental data, and publication-quality documentation.
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Ability to analyze and interpret laboratory data in support of diagnostic investigations, research studies, assay evaluation, and outbreak-response activities.
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Strong written and oral communication skills for training laboratory personnel, presenting research findings, and contributing to reports, manuscripts, and scientific presentations.
Requirements
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Bachelors in microbiology, virology, immunology, molecular biology, biological sciences, or a closely related scientific field.
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2-5 years of relevant experience.
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Ability to obtain and maintain CDC Public Trust Clearance.
Preferred Qualifications
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Masterβs degree in microbiology, virology, immunology, molecular biology, biological sciences, or a closely related scientific field.
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Approximately 3β5 years of relevant laboratory experience in viral diagnostics, immunology, infectious disease research, public health laboratory science, or related areas.
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Direct experience performing DFA, RFFIT, virus-neutralization, fluorescent antibody, or other rabies-related diagnostic and serologic assays.
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Experience evaluating humoral or cellular immune responses following vaccination or infection.
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Experience conducting diagnostic or research activities in BSL-3 laboratories and working with zoonotic or emerging viral pathogens.
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Experience participating in or coordinating animal studies involving viral inoculation, specimen collection, and laboratory testing.
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Experience propagating, purifying, characterizing, or maintaining rabies virus, orthopoxviruses, or other viral isolates.
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Experience performing nucleic acid extraction and testing of animal specimens potentially infected with zoonotic agents.
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Experience training laboratory staff or external partners in diagnostic assays, including international laboratory capacity-building or technical-assistance activities.
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Experience contributing to manuscripts, abstracts, peer-reviewed publications, or presentations at national or international scientific conferences.
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Prior experience with CDC.
Benefits
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Competitive base salary commensurate with your qualifications and experience.
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Comprehensive benefits package, including medical, dental, and vision insurance.
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401(k) plan with company matching.
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Tax-deferred savings options.
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Supplementary benefits.
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Paid time off.
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Professional development opportunities.