[Hiring] Research Scientist @Certara

Role Description

We have an opening for a highly motivated Research Scientist to work on research and development of mechanistic models for small and large molecules implemented within various Simcyp products. The Scientist will apply physiologically based pharmacokinetic (PBPK) modelling and in vitro-in vivo extrapolation (IVIVE) approaches to translate in vitro, preclinical and clinical data into predictive models for both small molecules and biologics.

• Active involvement in research and development of PBPK/PD models implemented within the Simcyp Simulators including collating, reviewing and analysing healthy and disease populations as well as compound and clinical data.
• Preparing implementation documents and developing case studies under guidance or independently leading wish-list and/or strategic projects as needed.
• Contributing to consultancy projects when required.
• Applying your experience/expertise in assisting with development and enhancement of IVIVE and PBPK modules.
• Flexibility to learn and work on projects in areas outside of your previous experience e.g., absorption modules when required.
• Training up to act as a tutor for Simcyp workshops when and if needed.
• Take on a substantial role in testing the Simulators before and after the release.
• Disseminating the outcome of research as poster/podium presentations and scientific publications.
• Communicating with clients and dealing with clients’ queries.
• Taking part in clients’ site visits and on-site education.
• Assisting with the research and development of externally funded projects e.g., grants.
• Maintaining an active interest and awareness of new research and technologies relevant to the field, expanding your field expertise, and disseminating these within the team.

Qualifications

• An MSc with at least 3 years of relevant experience, a PhD with at least 1 year of experience, in Pharmaceutical Sciences, Pharmacology, Pharmacokinetics, Biological/Biomedical Sciences, Chemical or Biochemical Engineering, or a related discipline, with a demonstrable background in PBPK modelling.
• Essential:
  • Evident experience in collating, reviewing and analysing literature data.
  • In-depth understanding and hands-on experience in in vitro to in vivo extrapolation techniques and PBPK modelling.
  • Excellent communication skills, as evident by presentation at scientific meetings, and good interpersonal and organizational skills.
• Desirable:
  • Familiarity with modelling and simulation principles of physiological and biological systems.
  • Good working knowledge of common or specialised modelling and simulation tools, such as Matlab, R, Phoenix, Simcyp, etc.
  • Familiarity with AI tools and their applications.
  • Experience in drug discovery and development within the pharmaceutical industry is desirable.

Company Description

Certara accelerates the potential of bringing medicines to market and to patients using biosimulation software, technology, and services to transform traditional drug discovery and development. Our clients include more than 2,400 biopharmaceutical companies, academic institutions, and regulatory agencies across 70 countries.

Our goal is to enable the life sciences industry’s use of data, modeling, and analytics to make better decisions across the various phases of discovery and drug development.