[Hiring] Vice President, Head of Immunology and Inflammation Development @Generate Biomedicines

Role Description

Generate:Biomedicines is seeking an experienced and strategic drug developer and people leader to guide our late-stage Immunology and Inflammation (I&I) programs. Reporting directly to the Chief Medical Officer I&I, this senior business leader will shape integrated development strategies and lead cross-functional teams from late-stage clinical development through regulatory submission and approval.

The successful VP, Head of I&I candidate will:

• Recruit, build, and develop a high-performing team of physicians and scientists.
• Create clear accountability while enabling strong collaboration across Clinical Operations, Safety, Regulatory, Biometrics, Translational Sciences, and other key functions.
• Be accountable for the design and delivery of rigorous late-phase development programs.
• Ensure scientific and clinical excellence, robust safety oversight, data integrity, and alignment with the company’s broader strategy.

The ideal candidate is an MD, MD/PhD, or PhD with significant biopharmaceutical industry experience in immunology and a demonstrated track record of strategic drug development, executional excellence in pivotal trials, and building and leading high-performing teams.

Here's how you will contribute:

• Lead a high performing Product Strategy Team (PST) comprised of cross-functional leaders accountable for setting the strategy for the late stage I&I programs.
• Develop high quality, ambitious development plans aligned with late-stage and corporate objectives and compliant with all relevant regulations.
• Recruit, mentor and develop a team of late-stage clinicians and scientists.
• Collaborate with Head of Safety and PV to define risk-benefit profiles.
• Collaborate with Clinical Operations and CRO to deliver study to timelines and budget.
• Lead programs through registration development and BLA readiness, ensuring clinical strategy, evidence generation, and execution support successful global regulatory submissions.
• Drive development and refinement of Target Product Profiles (TPPs), Target Product Claims, and clinical development strategies.
• Guide interactions with external stakeholders including KOLs, advisory boards, and CROs.
• Represent Generate externally at scientific, medical, and regulatory meetings.
• Provide medical leadership and awareness of evolving external landscape for late-stage clinical trials in respiratory diseases.

Qualifications

• MD, MD/PhD, or PhD is required.
• Board certification in Pulmonology, Allergy and Immunology, or Rheumatology is preferred but not required.
• 10+ years of drug development experience in the biopharma industry.
• 4+ years direct people management experience in industry.
• Deep expertise in global late-stage (Phase III) clinical trials.
• Prior experience leading a cross-functional clinical development team through pivotal development and successful BLA/NDA submission.
• Demonstrated success in leading pivotal global studies and regulatory interactions.
• Strong analytical, communication, and cross-functional leadership skills.
• Proven ability to influence internal and external stakeholders, including investors, investigators, and health authorities.

Nice to Have (Optional)

• Previous work in both large pharma and biotech settings.
• Respiratory experience in clinical practice, Medical Affairs, Clinical Development or as Project Leader.

Location

Somerville, MA / Andover, MA; remote (U.S.) optional with travel to HQ based on business needs.

Benefits

This is a rare opportunity to shape the future of immunology and inflammation medicine at a company pioneering Generative Biology™. You’ll be empowered to lead transformative trials in a collaborative, mission-driven environment, surrounded by relentless problem solvers who are reimagining what’s possible in drug discovery and development. You’ll have the scope, visibility, and autonomy to influence both the success of the portfolio and the capabilities of the organization, working alongside ambitious, collaborative leaders who are reimagining how medicines are discovered and developed for patients with significant unmet needs.

Compensation

The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.

• Per Year Salary Range: $335,000 - $435,000 USD