[Hiring] Medical Director - Heart Failure @Pharmacosmos Therapeutics Inc

Role Description

This role offers the opportunity to help shape Pharmacosmos’ future presence in heart failure while supporting one of the company’s most important clinical development programs. The role sits at the interface of Clinical Development and Medical Affairs and has two complementary objectives:

• Support successful execution and patient recruitment of the ICONIC-HF trial in the United States through investigator engagement, site support, insight generation, and identification of barriers to study execution.
• Build the scientific, stakeholder, and market foundation for future IV iron adoption in heart failure, including KOL engagement, strategic insight generation, advocacy development, launch readiness, and future medical-marketing support.

The successful candidate will work closely with both the US affiliate and global headquarters in Denmark and will have regular interaction with cross-functional leadership teams across Clinical Development, Medical Affairs, Strategy and Operations, and Market Access. The role is intended for an individual who enjoys combining scientific engagement, strategic thinking, and execution in a highly collaborative global environment.

Job Responsibilities

The responsibilities are structured in two complementary pillars:

1. Trial Support: ICONIC-HF Site Engagement and Enrollment Enablement

• Establish and maintain strong scientific relationships with investigators, study coordinators, and other site personnel involved in ICONIC-HF.
• Conduct regular site engagements, virtually and in person where relevant, to understand local opportunities, challenges, operational barriers and operate within compliance, GCP, and trial governance frameworks.
• Serve as a US-based scientific liaison between participating sites and the HQ R&D ICONIC-HF trial team in coordination with the US affiliate and the contracted CRO.
• Identify, understand, and communicate barriers that may impact screening, enrollment, site engagement, or study execution, analyze potential root causes, and help define mitigations activities with HQ R&D ICONIC-HF trial team and the CRO.
• Facilitate appropriate cross-functional problem solving and escalation pathways when barriers are identified.
• Support protocol understanding and scientific discussions within approved governance frameworks.
• Gather and communicate investigator insights, competitive intelligence, protocol feedback, and study-related observations to internal stakeholders.
• Organize and facilitate regional sponsor-investigator touchpoint meetings as appropriate.
• Identify and share best practices from successful sites to support broader site engagement efforts, where appropriate and compliant.
• Support site activation and engagement initiatives in partnership with HQ R&D ICONIC-HF trial team and the CRO.
• Maintain a strong understanding of site experiences and investigator perspectives throughout the study lifecycle.

Boundaries of the Role:

• Does not function as a CRA.
• Does not perform monitoring activities.
• Does not conduct source data verification.
• Does not own enrollment metrics or site performance targets.
• Does not manage day-to-day clinical trial operations.

2. Strategic Heart Failure Insights, Advocacy Development and Launch Readiness

• Develop a deep understanding of the evolving US heart failure landscape, including treatment pathways, referral patterns, unmet needs, evidence gaps, barriers to adoption, and emerging trends relevant to IV iron.
• Map, prioritize, and engage regional and national heart failure thought leaders.
• Build and maintain scientific relationships with key experts beyond the ICONIC-HF investigator network.
• Generate actionable insights that can support future evidence generation, publication planning, congress activities, scientific communication, advisory board strategy, and launch readiness.
• Partner closely with HQ and the US affiliate to ensure field insights are translated into strategic recommendations.
• Support identification and prioritization of investigator-sponsored research opportunities.
• Contribute to long-term medical affairs strategy and launch-readiness planning for IV iron in heart failure.
• Support future launch-readiness initiatives through close partnership with Medical Affairs, Strategy and Operations, Market Access, and Commercial colleagues while maintaining full compliance with applicable governance requirements.

Qualifications

• Advanced scientific or healthcare degree preferred, e.g., MD, PharmD, PhD, NP, PA, MSc, or equivalent.

Requirements

• Experience within cardiology is required; heart failure experience is preferred.
• Experience from clinical development, research and/or Medical Affairs.
• Demonstrated understanding of clinical trial conduct and investigator engagement.
• Experience collaborating with investigators, academic institutions, and cross-functional internal stakeholders.
• Ability to work effectively within cross-functional and matrix organizations.
• Strong scientific communication, relationship-building, and stakeholder-management skills.
• Ability to translate external insights into actionable recommendations for internal stakeholders.
• Basic GCP training or certification is preferred. Training can be provided for an otherwise qualified candidate.

Additional Preferred Experience

• Heart failure expertise.
• Cardiovascular outcomes trial experience.
• Launch or pre-launch experience.
• Experience engaging US-based KOLs and national thought leaders.
• Experience working across both clinical development and medical affairs environments.
• Established KOL network within heart failure/cardiology.

Success Profile

The ideal candidate combines scientific credibility with strategic thinking and strong interpersonal skills. They are equally comfortable discussing heart failure science with leading investigators, understanding operational challenges that affect study execution, generating insights from the external environment, and translating those insights into recommendations that influence US and global strategy. They enjoy working in a collaborative environment and are motivated by the opportunity to help shape both the successful execution of ICONIC-HF and the future development of a US heart failure franchise.

Competencies

• Proud Pharmacosmos ambassador
• Strong personal leadership
• Inspire cross-functional transparency and collaboration
• Customer-centric ‘can-do’ attitude and goal focused
• Ambitious, independent, analytical, collaborative, loyal, organized
• Exemplifies Medical Affairs TRAC (Trust, Respect, Accountability, Collaboration) values

Additional Information

• Requires budgetary responsibilities and discretion with confidential data.
• Travelling – approximately 65% of the time.