[Hiring] Medical Director @Jade Biosciences

Role Description

We are seeking an experienced and mission-driven Medical Director to lead and support clinical programs in nephrology, with a focus on rare or immune-mediated kidney diseases. This role is ideal for a physician-scientist who thrives in a small biotech environment where agility, cross-functional collaboration, and scientific leadership are essential. The Medical Director will play a key role in advancing Jade’s pipeline through clinical development. This newly created position will report to the Executive Medical Director of Clinical Development. This is a fully remote role and will require some travel.

Key Responsibilities

• Lead the design, execution, and oversight of clinical trials in nephrology, including protocol development, study monitoring, and data interpretation.
• Serve as Medical Monitor for ongoing trials, ensuring patient safety and scientific integrity.
• Collaborate with clinical operations, regulatory, and biometrics teams to ensure trial success and compliance.
• Educate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and/or site initiation visits, and serving as the medical point of contact for site staff questions about patient eligibility, and providing input into patient safety assessment and management.
• Provide medical expertise and support to external partners, vendors, and contractors as required to ensure smooth program execution.
• Communicate effectively, orally and in writing, with internal and external stakeholders regarding the assigned clinical program, including the CMO, CEO, external medical experts, and others.
• Contribute to the preparation of regulatory documents (INDs, NDAs, briefing documents, etc.).
• Support interactions with regulatory authorities and ethics committees.
• Stay current with scientific literature and competitive landscape in nephrology and related fields.
• Partner with translational science, biomarker, and commercial teams to align clinical strategy with broader company goals.
• Provide medical input into lifecycle planning and early market preparation.
• Begin building relationships with key opinion leaders (KOLs), investigators, and advocacy groups in nephrology.
• Represent the company at scientific meetings, advisory boards, and industry events.

Qualifications

• MD (or equivalent medical degree); board certification in nephrology strongly preferred.
• 3+ years of experience as a nephrologist in academia or industry, and/or experience in nephrology clinical trials or rare disease programs.
• Experience in clinical trial design, execution, and medical monitoring.
• Strong clinical judgment, scientific rigor, and regulatory knowledge.
• Ability to work independently and thrive in a fast-paced, matrixed environment.
• Ability to manage multiple projects simultaneously and prioritize effectively in a fast-paced environment.
• Strong analytical, problem-solving, and decision-making skills.
• Excellent communication and interpersonal skills with the ability to influence and motivate cross-functional teams, manage a diverse set of stakeholders, and work closely with team leaders.
• High ethical standards and impeccable integrity.
• Exercise sound judgment in managing complex, confidential, and regulated information.

Requirements

• This is a remote role; periodic travel to team and company events is required.
• The anticipated salary range for candidates for this role is $270,000 - $300,000.
• The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.

Company Description

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development.