Back to Remote jobs  >   AI / ML
Senior Lead Machine Learning Engineer @Upwork
AI / ML
Salary $195,000 - $296..
Remote Location
🇺🇸 USA Only
Job Type full-time
Posted 2mths ago

[Hiring] Senior Lead Machine Learning Engineer @Upwork

2mths ago - Upwork is hiring a remote Senior Lead Machine Learning Engineer. 💸 Salary: $195,000 - $296,000 usd 📍Location: USA

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more.

Role Description

We’re seeking a Senior Lead Machine Learning Engineer to play a pivotal role in shaping the future of AI-powered intelligence at Upwork. In this high-impact role, you’ll lead the design and delivery of infrastructure and models that support agentic LLM workflows across our platform. Your work will span from research to production, empowering teams and driving innovation that delivers measurable business results.

This is more than a technical leadership role—it’s an opportunity to guide strategy, mentor others, and represent Upwork in the broader AI/ML community. You’ll architect scalable ML systems, guide cross-functional initiatives, and help define the next generation of autonomous AI agents.

  • Design and implement resilient infrastructure for agentic LLM systems, including multi-agent coordination, Retrieval-Augmented Generation (RAG), and real-time orchestration.
  • Lead training and fine-tuning of large-scale foundation models tailored to Upwork’s domain-specific challenges and user base.
  • Partner with engineering, product, and research teams to align technical development with strategic business priorities.
  • Mentor and support other engineers and researchers to elevate team-wide technical capabilities and foster a culture of innovation and inclusion.
  • Drive experimentation and translate findings into robust, scalable production systems with clear metrics of success.
  • Identify opportunities for innovation, challenge conventional approaches, and lead initiatives that push the boundaries of applied ML.
  • Contribute to the external AI/ML community through papers, talks, or open-source contributions, enhancing Upwork’s visibility in the field.

Qualifications

  • Demonstrated expertise in building, deploying, and scaling advanced ML models in a production environment using Python and frameworks like PyTorch or TensorFlow.
  • Deep technical understanding of transformer-based models, generative AI, and agent architectures such as MCP or A2A.
  • Proven experience training and optimizing large models on GPU clusters and integrating LLMs with APIs or orchestration systems.
  • Track record of leading high-impact, cross-functional initiatives with a focus on business outcomes and customer value.
  • A collaborative mindset, clear communication skills, and a drive to mentor and elevate those around you.

Benefits

  • Comprehensive medical coverage for you and your family
  • Unlimited PTO
  • 401(k) plan with matching
  • 12 weeks of paid parental leave
  • Employee Stock Purchase Plan

Company Description

Upwork ($UPWK) is the world’s human and AI-powered work marketplace that connects businesses with highly skilled, AI-enabled independent talent from across the globe. From entrepreneurs to Fortune 100 enterprises, companies rely on Upwork’s trusted platform and its mindful AI companion, Uma, to find and hire expert talent, leverage AI-powered work solutions, and drive business transformation.

Upwork’s platform has facilitated more than $25 billion in economic opportunity for talent around the world.

Before You Apply
🇺🇸 Be aware of the location restriction for this remote position: USA Only
Beware of scams! When applying for jobs, you should NEVER have to pay anything. Learn more.
Back to Remote jobs  >   AI / ML
Senior Lead Machine Learning Engineer @Upwork
AI / ML
Salary $195,000 - $296..
Remote Location
🇺🇸 USA Only
Job Type full-time
Posted 2mths ago
Apply for this position Unlock 85,418 Remote Jobs
🇺🇸 Be aware of the location restriction for this remote position: USA Only
Beware of scams! When applying for jobs, you should NEVER have to pay anything. Learn more.
Apply for this position Unlock 85,418 Remote Jobs
×
  • Unlock 85,418 hidden remote jobs.
  • Your shortcut to remote work. Apply before everyone else.
  • Click and apply. No middlemen, no hassle.
  • Filter by location/skills/salary…
  • Create custom email alerts
Unlock All Jobs Now