[Hiring] Global Enrollment Systems Lead @Massive Bio

Role Description

This role involves designing and optimizing the operational engine that converts AI-matched patients into randomized trial participants at scale.

• Own enrollment velocity end to end
• Map the full funnel from qualification → site referral → screening → consent → randomization
• Identify bottlenecks and drop-offs
• Reduce cycle time
• Increase throughput without proportional headcount growth
• Build scalable playbooks across countries

You will work across internal teams (AI, clinical operations, customer success) and external stakeholders (sites, sponsors, CROs, networks) to eliminate friction and maximize conversion.

This is a high-autonomy role with direct exposure to leadership and co-founders. As volume scales, you will build and lead a team to expand operational capacity.

Think like an industrial engineer inside one of the most complex operational systems in healthcare.

• Map and continuously refine the enrollment value stream
• Build dashboards tracking funnel performance at each stage
• Analyze conversion drop-offs and variance by country, site, and trial
• Model capacity constraints and identify system bottlenecks
• Reduce match-to-randomization cycle time
• Standardize scalable enrollment playbooks across regions
• Align AI outputs with real-world operational execution
• Improve screen failure rates through structured pre-qualification systems
• Increase enrollment throughput per FTE
• Create operational leverage as we grow

This is a live, multi-country, multi-stakeholder system — not a theoretical exercise.

Success Metrics (You Own These)

• % reduction in match-to-randomization cycle time
• Improvement in qualification-to-screening conversion
• Reduction in screen failures
• Increase in enrollment throughput per trial
• Capacity scaling without linear headcount growth
• Country-level velocity optimization
• Funnel transparency through performance dashboards

Enrollment speed is the product. You own it.

Who This Role Is For

• Thinks in systems, bottlenecks, and throughput
• Has led end-to-end operational pipelines in high-growth environments
• Loves reducing friction and optimizing complexity
• Builds dashboards and makes decisions based on data
• Is comfortable operating with ambiguity and building new functions
• Thrives in startup environments without bureaucracy
• Wants ownership, not supervision

You might come from:

• Industrial engineering
• Operations in logistics or supply chain
• High-growth tech startups
• Healthcare services
• Consulting (operations focus)
• Private equity portfolio operations
• Clinical trials operations with a strong systems mindset

Required Experience

• 5–8 years leading operational delivery in complex, multi-stakeholder environments
• Demonstrated ownership of a conversion funnel or delivery pipeline end to end
• Experience improving throughput and reducing cycle time systematically
• Track record of scaling an operational function without linear headcount growth
• Strong analytical capability (Excel, dashboards, data modeling, PowerPoint)
• Structured project management discipline across multiple parallel workstreams
• High energy and resilience in fast-moving startup environments

Strongly Preferred

• Healthcare, life sciences, or clinical trials experience
• Oncology knowledge (biomarker testing, treatment sequencing)
• Experience working with AI-enabled platforms
• Familiarity with patient recruitment vendors or CRO operations
• PMP or similar structured project management training

Why This Role Is Different

You are not inheriting a mature, slow-moving department. You are building the enrollment operating system for a global AI-enabled oncology platform.

Every week of cycle time reduction accelerates access to life-saving therapies. Within 12–18 months, this role is expected to evolve into a broader operational leadership position as you build and lead your own team.

If you get energy from turning complexity into scalable systems — and want your optimization work to directly impact cancer patients worldwide — this is your arena.