[Hiring] Vice President, Clinical Pharmacology & Pharmacometrics @Recursion

Role Description

Your work will change lives. Including your own.

As Vice President, Clinical Pharmacology & Pharmacometrics, you will set the enterprise strategy for clinical pharmacology, pharmacometrics, and model-informed drug development across Recursion’s advancing clinical portfolio.

You will be accountable for translating nonclinical, translational, biomarker, clinical, and quantitative data into development decisions that help us select the right dose, regimen, population, and study design for each program. Your team will bring together expertise across:

• Clinical Pharmacology
• Pharmacometrics
• Translational Modeling
• Preclinical PK/PK-PD

This is a highly strategic leadership role for a clinical pharmacology leader who can operate from first-in-human planning through registrational development, regulatory submission, and label strategy. You will:

• Set the enterprise strategy for Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical-to-clinical quantitative integration across Recursion’s clinical and post-candidate nomination portfolio.
• Own dose strategy from first-in-human planning through registrational development, including dose escalation, dose optimization, exposure-response, safety, efficacy, and label-supporting dose justification.
• Lead quantitative development approaches, including population PK, PK/PD, exposure-response, PBPK, QSP, disease progression modeling, and clinical trial simulations.
• Design and oversee clinical pharmacology studies, including food effect, DDI, organ impairment, QT/cardiac safety, bioavailability/bioequivalence, mass balance/ADME, and special population studies.
• Partner cross-functionally with Clinical Development, Development Sciences, DMPK, Toxicology, Translational Modeling, Biomarkers, Regulatory, Biostatistics, CMC, and Data Science to inform development strategy and decision-making.
• Represent Recursion as the clinical pharmacology expert in regulatory interactions and ensure high-quality clinical pharmacology contributions to INDs/CTAs, briefing books, NDAs/BLAs/MAAs, regulatory responses, and labeling.
• Represent Clinical Pharmacology and Translational Modeling in cross-functional program teams, governance forums, regulatory interactions, and alliance settings with Recursion’s external pharma partners.
• Build, mentor, and scale a high-performing Clinical Pharmacology and Pharmacometrics function, including internal talent, consultants, CROs, and external modeling partners.
• Advance the responsible use of AI, automation, and advanced analytics to improve evidence integration, modeling workflows, and clinical development decisions.

Qualifications

• Advanced degree in clinical pharmacology, pharmacometrics, pharmaceutical sciences, quantitative pharmacology, biomedical engineering, medicine, pharmacy, or a related field; PhD, PharmD, or MD preferred.
• 15+ years of biotech or pharmaceutical industry experience, including significant leadership experience in Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, or model-informed drug development.
• Proven success leading clinical pharmacology strategy across multiple programs, ideally from first-in-human studies through registrational development, submission, and labeling.
• Deep expertise in PK, PK/PD, exposure-response, exposure-safety, population PK, PBPK, QSP, dose optimization, dose justification, and model-based clinical trial design.
• Experience designing, interpreting, and defending clinical pharmacology studies and analyses in support of global development and regulatory submissions.
• Strong understanding of FDA, EMA, MHRA, PMDA, and ICH expectations for clinical pharmacology, pharmacometrics, dose selection, MIDD, and regulatory documentation.
• Demonstrated ability to build and lead high-performing teams, influence senior stakeholders, manage external partners, and communicate complex quantitative concepts clearly to executives, program teams, partners, and regulators.
• Experience in oncology, rare disease, and/or small molecule development strongly preferred; experience applying AI, advanced analytics, or automation in clinical pharmacology is a plus.

Requirements

• Making NYC your home base is ideal, however, we will consider remote work for this position. Remote employees must commit to regular on-site visits for routine work and departmental events.
• Estimated annual base salary range for New York City, San Francisco Bay Area, & Boston area(s): $353,980 to $443,080.
• Estimated annual base salary range for all other US locations: $321,800 to $402,800.
• This role is eligible for an annual bonus, equity compensation, and a comprehensive benefits package.

Benefits

• Comprehensive benefits package.
• Annual bonus eligibility.
• Equity compensation.

Company Description

Recursion (NASDAQ: RXRX) is a clinical-stage TechBio company decoding biology to radically improve lives. Recursion is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need.

Enabling its mission is the Recursion OS, an AI-native, end-to-end drug discovery and development platform integrating biology, chemistry, and clinical development into a unified intelligence system.

Recursion’s platform infrastructure is anchored in Salt Lake City, Utah and Milton Park, Oxfordshire, where its automated biology and chemistry laboratories generate proprietary data at industrial scale. Recursion also maintains offices in New York, Montréal, and London.