Role Description
This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
Praxis is seeking a Senior Medical Science Liaison (Sr. MSL) to lead and develop a team of Medical Science Liaisons (MSLs) supporting pre-launch and launch activities for ulixacaltimide in movement disorders. This is a hands-on leadership role responsible for:
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Building, coaching, and directing a high-performing field medical team.
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Maintaining strategic engagement with key investigators, movement disorder specialists, and other neurology stakeholders.
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Translating medical strategy into field execution.
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Ensuring high-quality scientific exchange and driving clinical and account readiness.
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Partnering cross-functionally with Medical, Clinical Development, Commercial, and Market Access teams.
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Translating field insights into actionable strategic recommendations.
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Field team effectiveness, including performance management, territory alignment, and resource deployment.
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Reporting directly to the Head of Field Medical Affairs.
Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast-paced environment.
Qualifications
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Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN).
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Experience in medical affairs, clinical research, clinical care, or field-based roles within biotech/pharma.
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Demonstrated ability to interpret, communicate, and translate complex scientific and clinical data into clear, actionable insights.
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Strong ownership mindset with the ability to operate independently and navigate ambiguity.
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Proven ability to build and maintain trusted relationships with healthcare professionals.
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Experience gathering, synthesizing, and translating field insights into actionable recommendations.
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Ability to manage multiple priorities with strong organizational skills.
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Willingness and ability to travel extensively (~60โ80%).
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Demonstrated experience leading, coaching, and developing field-based teams.
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Proven ability to translate medical strategy into effective field execution.
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Experience influencing cross-functional stakeholders in a matrixed environment.
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Experience in neurology, CNS disorders, or movement disorders is preferred.
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Experience within market access/payor landscape is preferred.
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Demonstrated ability to rapidly develop expertise in new therapeutic areas.
Requirements
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Candidates with prior field-based experience and a demonstrated track record of independently driving scientific engagement will be considered at a higher level.
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Candidates with prior experience leading MSL teams and supporting product launches will be considered at the Director level.
Benefits
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99% of the premium paid for medical, dental, and vision plans.
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Company-paid life insurance, AD&D, disability benefits, and voluntary plans.
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Dollar-for-dollar match up to 6% on eligible 401(k) contributions.
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Long-term stock incentives and ESPP.
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Discretionary quarterly bonus.
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Flexible wellness benefit.
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Generous PTO, paid holidays, and company-wide shutdowns.
Company Description
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Our core values of Trust, Ownership, Curiosity, and Results are foundational to every aspect of our business.
Guided by our core values, we continue to DARE FOR MOREยฎ to advance, promote, and champion diversity, equity, and inclusion.