[Hiring] Senior Director of Medical Affairs, Pipeline Lead @Ultragenyx Pharmaceutical

Role Description

Ultragenyx is seeking a dynamic and experienced leader to join the Global Medical Affairs team with responsibility for the pipeline portfolio. The Sr. Director, Pipeline Lead will provide strategic early medical affairs leadership across multiple early-stage assets in our neurology and inborn errors of metabolism portfolios, including:

• GNE Myopathy
• Creatine Transporter Deficiency
• Wilson’s Disease
• Ornithine Transcarbamylase Deficiency

This role requires an adaptable leader willing to take a “hands-on” approach in their work and who is comfortable working in a fast-paced intellectual environment.

Work Model: Remote: Officially documented as working full-time from home, with travel to Ultragenyx's offices or other locations on occasion as needed.

Responsibilities

• Provide early medical affairs leadership to assigned programs, serving as an active core member of the Program Team and decision-making sub-teams, and contributing to the progression of program milestones.
• Demonstrate and apply deep rare disease expertise across assigned programs, actively building and maintaining a global network of therapeutic area experts.
• Lead insight-generation activities, including scientific advisory boards and steering committees that inform program strategy.
• Lead the development of an aligned early-stage Integrated Evidence Generation Strategy for assigned programs, incorporating real-world evidence generation.
• Lead proactive competitive landscape assessments and translate emerging science and therapeutic area dynamics into strategic recommendations for asset positioning.
• Establish and lead the Global Medical Sub Team(s), and drive the development and implementation of the medical strategy for assigned pipeline programs.
• Partner with scientific and medical communications to guide development of the end-to-end scientific communication platform.
• Ensure timely and effective data dissemination by leading publication strategies, congress planning, and scientific education initiatives.
• Provide deep disease area and product expertise, ensuring accurate and consistent communication of clinical and scientific data.
• Provide guidance, tools, and high-quality compliant training to US field and regional medical affairs teams.
• Collaborate effectively with clinical development, HEOR, diagnostics, scientific and medical communications and publications, regulatory, market access, commercial, training, and patient advocacy.

Qualifications

• Advanced medical/scientific degree (MD, DO, PhD, PharmD) (required).
• Minimum 7 years of experience in Medical Affairs (required); global experience is strongly preferred.
• Proven track record in pipeline strategy, evidence generation, and external engagement.
• Experience and comfort operating across early-phase development programs spanning multiple disease areas.
• Strong collaboration and stakeholder management skills; adept at functioning in a highly matrixed environment.
• Recognized scientific authority with the ability to engage in advanced scientific and clinical discussions with both internal and external experts.
• High aptitude for attention to detail, commitment to high-quality work, and a sense of passion and urgency to achieve goals and improve the lives of patients.
• Highly analytical and strategic thinker with the ability to identify interdependencies and understand the broader goals of a program.
• Excellent communication skills, with the ability to effectively articulate scientific and strategic concepts in both written documents and verbal presentations.
• Travel estimated up to 15%.

Requirements

• Advanced medical/scientific degree (MD, DO, PhD, PharmD) (required).
• Minimum 7 years of experience in Medical Affairs (required); global experience is strongly preferred.

Benefits

• Generous vacation time and public holidays observed by the company.
• Volunteer days.
• Long term incentive and Employee stock purchase plans or equivalent offerings.
• Employee wellbeing benefits.
• Fitness reimbursement.
• Tuition sponsoring.
• Professional development plans.
• Benefits vary by region and country.