[Hiring] Senior Director, Medical Affairs, Neurology/CNS @Praxis Precision Medicines, Inc.

Role Description

This is a rare opportunity to step into a high-impact role to shape and lead Medical Affairs strategy across a growing CNS/Neurology portfolio at Praxis. We are seeking a Senior Director, Medical Affairs, to play a strategic leadership role spanning late-stage development through post-marketing. This individual will have the opportunity to influence both disease-area strategy and long-term portfolio direction, with meaningful exposure to executive leadership and cross-functional teams and decision-making. You’ll establish and maintain strong relationships with the medical and scientific community, including key opinion leaders and patient advocacy organizations, to support scientific exchange, inform strategy, and identify emerging medical and healthcare trends.

This role will focus across Neurology indications, including Epilepsy and Movement Disorders, with flexibility to align therapeutic ownership based on experience and business needs. If you are looking for a role with true strategic ownership, internal and external visibility, and the ability to build and shape, this is a uniquely compelling opportunity.

Primary Responsibilities

• Serve as the Medical Affairs leader for Neurology, representing Praxis internally and externally with KOLs, investigators, and advocacy organizations.
• Lead the development and execution of integrated medical strategy across the product lifecycle (late-stage through post-marketing).
• Shape disease-state strategy, scientific exchange, and evidence generation plans.
• Design and execute key initiatives including advisory boards, congress strategy and engagement, publication planning, field medical strategy.
• Build and maintain strong relationships with external stakeholders, including KOLs, academic institutions, and patient advocacy groups.
• Partner cross-functionally with Clinical Development, Commercial, Regulatory, and other key functions to ensure alignment and impact.
• Lead Investigator-Initiated Studies (IIS) and company-sponsored research strategy.
• Oversee vendors, budgets, and operational execution with a focus on quality and compliance.

Qualifications

• Advanced degree: MD/DO, PharmD, or PhD with strong relevant experience in Neurology/CNS - such as Epilepsy, Movement Disorders, or adjacent indications.
• 10+ years of experience in Medical Affairs and/or in combination with Clinical Research, within a Biotechnology/Pharmaceutical Organization.
• Demonstrated leadership experience at the Director or Senior Director or equivalent level, with the ability to lead strategy within Medical Affairs.
• Proven ability to organize and lead scientific advisory panels, foster KOL relationships, and to clearly communicate complex scientific and medical information to both internal and external stakeholders.
• Solid understanding of U.S. regulations governing Medical Affairs activities.
• Experience across product lifecycles, from late-stage clinical development through post-marketing strategy and safety monitoring.

Requirements

• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.
• You'll need comfort with screen work, basic hand coordination, and focus.
• Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Benefits

• World-class benefits package including 99% of the premium paid for medical, dental and vision plans.
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage.
• Dollar-for-dollar match up to 6% on eligible 401(k) contributions.
• Long-term stock incentives and ESPP.
• Discretionary quarterly bonus, flexible wellness benefit, generous PTO, paid holidays, and company-wide shutdowns.
• A collaborative work environment with smart, engaged, and inspiring colleagues.

Company Description

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis, we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.

• Core Values: Trust, Ownership, Curiosity, and Results.
• Commitment to diversity, equity, and inclusion.