[Hiring] Senior Director, Epidemiology @Revolution Medicines

Role Description

The Senior Director, Epidemiology is responsible for leading the strategy and execution of epidemiology plans and activities for Revolution Medicines assets and/or indications. They will be accountable for working across the clinical development, safety, medical affairs, and commercial matrix developing strategies and overseeing execution of key epidemiology deliverables.

• Lead the epidemiology strategy for a given asset and/or indication.
• Develop plans for epidemiology deliverables, including:
  • Systematic literature reviews
  • Natural history studies
  • Clinical trial design and optimization
  • Comparative effectiveness and safety
  • Post-approval safety studies
  • Healthcare resource utilization analyses
• Design and execute deliverables in accordance with the plan, either personally or through oversight of other epidemiologists/vendors/contractors.
• Provide epidemiology leadership to Clinical Development, Global Patient Safety, Regulatory Affairs, Medical Affairs, and Commercial activities across the medicines development life cycle.
• Ensure epidemiology point of view is included in key deliverables from other functions.
• Lead activities related to scientific manuscripts, clinical conference abstracts, presentations, and posters based on observational study data.
• Represent HEOR/RWE department during interactions with key external stakeholders.
• Appraise and synthesize relevant epidemiological and RWE literature and regulatory guidance documents.

Qualifications

• PhD / DSc / DrPH in epidemiology or a relevant advanced science degree.
• At least 12 years of related industry experience at a sponsor/pharmaceutical company.
• Demonstrated technical knowledge of pharmacoepidemiologic methods and real-world oncology data sets.
• History of publications demonstrating the successful design, execution, and communication of epidemiologic research.
• Knowledge of drug and clinical development process for genomic/targeted medicines.
• Excellent analytic and problem-solving skills.
• Excellent attention to detail and quality, and scientific rigor.
• Strong interpersonal skills and the ability to work effectively in multidisciplinary teams.
• Existing external relationships to foster collaborative and timely research.

Requirements

• 12+ years of oncology pharmacoepidemiology experience at a sponsor/pharmaceutical company.
• Experience driving from conception to completion post-approval safety studies using RWD submitted to global regulators.

Benefits

• Competitive cash compensation.
• Robust equity awards.
• Strong benefits.
• Significant learning and development opportunities.

Company Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers.

• The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins.
• Current clinical development includes daraxonrasib (RMC-6236), elironrasib (RMC-6291), zoldonrasib (RMC-9805), and RMC-5127.