[Hiring] Pathology Senior Director @Amgen

Role Description

Join Amgen’s Mission of Serving Patients. Amgen is seeking a Pathology Senior Director within the Discovery and Toxicologic Pathology of Translational Safety Regulatory Science function. The role has a focus on digital pathology to accelerate the execution of computational pathology workflows inclusive of AI/ML model development discovery programs.

• Responsible for ensuring the reliable execution of computational pathology workflows, including FAIR data curation, quality control, and analysis activities.
• Ensures that imaging data, metadata, annotations, and analysis outputs are fit for purpose for AI development and scientific biologic conviction.
• Functions as a project pathologist, supporting the advancement of the pipeline by designing, executing, and interpreting toxicology studies.
• Assesses safety risks and contributes to project strategy across all phases of Research and Development, as well as for marketed products.
• Collaborates closely with Toxicology and Study Management and CRO partners.

Key Responsibilities

• Ensure incoming datasets are delivered according to defined data formats, metadata standards, and project requirements.
• Translate scientific and model development requirements into structured dataset preparation tasks with pathology scientists and pathologists.
• Ensure imaging data, annotations, and metadata are suitable for downstream AI/ML model development, validation, and scientific analysis.
• Execute computational pathology workflows across AI model development and discovery projects for image analysis workflows.
• Identify opportunities to improve data workflows, tooling, and operational processes within computational pathology.
• Stay informed about emerging data management practices, digital pathology technologies, and AI data standards.
• Provide pathology expertise to the design and conduct of GLP and non-GLP nonclinical safety studies.
• Serve as a contributing author to pathology sections of regulatory documents such as INDs, NDA/BLAs, IBs, and respond to Health Authority questions.

Qualifications

• DVM and 7 years of pathology or toxicology experience OR
• Master’s degree and 10 years of pathology or toxicology experience OR
• Bachelor’s degree and 12 years of pathology or toxicology experience.

Preferred Qualifications

• DVM, Board Certification in Veterinary Anatomic Pathology (DACVP or comparable credentialing body) and PhD in pathology or toxicology.
• At least 15 years’ experience in the pharmaceutical sector as a discovery and toxicologic pathologist.
• 5 years’ experience integrating pathology data into bioinformatics efforts in a pharmaceutical environment.
• Experience in pathology data management within pharmaceutical environments is highly desirable.
• Demonstrated experience working with large-scale imaging datasets and associated metadata in distributed or cloud environments.
• Experience with annotation platforms, digital pathology pipelines, or whole-slide image analysis environments.
• Familiarity with IHC assay workflows and digital slide scanning.
• Experience in interpreting target discovery pathology and toxicology studies.
• Strong problem-solving skills and solution-oriented mindset.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions.
• Group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.

Salary Range

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is 249,288.85 USD - 337,273.15 USD. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.