[Hiring] Manager, Clinical Biomarker Assays, Translational Science - Neuroscience @Arvinas

Role Description

We are seeking a highly motivated Manager, Clinical Biomarker Assays, Translational Sciences, Neuroscience with biomarker expertise to lead and execute clinical biomarker assay development, validation and implementation activities to support our neuroscience clinical programs. This individual will perform as the Clinical Biomarker Assay Lead within Translational Sciences to support Neuroscience programs, and will be responsible for:

• Clinical biomarker CROs evaluation and oversight
• Clinical biomarker assay development and validation
• Clinical sample testing execution
• High-quality biomarker data generation and transfer to support assessment of pharmacodynamics including target engagement, patient stratification, and disease progression

The successful candidate will combine strong scientific rigor with cross-functional leadership and a track record of overseeing development of biomarker assays for utilization in clinical studies. This position reports to Director, Translational Sciences – Neuroscience and can be located at our headquarters in New Haven, CT or work remotely from a location within the U.S.

Qualifications

• 5+ years (industry preferred) in clinical biomarker assay development and/or bioanalytical sciences
• Demonstrated experience managing external CROs and central laboratories
• Demonstrated experience with protein biomarkers (such as fluid (including CSF) and tissue biomarkers, blood-based biomarkers), and genomic platforms (e.g., Simoa, MSD, Olink, mass spectrometry, NGS)
• Experience with neuroimaging biomarkers (e.g., PET, MRI) and/or digital biomarkers preferred
• Familiarity with clinical data standards and biomarker data transfer processes
• Experience working in neuroscience and/or rare diseases such as Parkinson’s disease, PSP, Alzheimer’s disease, or related disorders preferred
• Experience supporting IND-enabling or early-phase clinical trials preferred
• Demonstrated success in working cross-functionally within multidisciplinary teams
• Excellent communication, organizational, and problem-solving skills, with the ability to operate independently in a matrixed environment

Requirements

• Arvinas will not be providing VISA sponsorship for this position. You must have the ability to work without a need for current or future VISA sponsorship
• The duties of this role are generally conducted in a combination of company office and home office environments
• Employees must be able, with or without an accommodation, to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours

Benefits

• Competitive package of base and incentive compensation
• Comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families
• Group medical, vision and dental coverage
• Group and supplemental life insurance
• And much more

Company Description

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins.

• Utilizes its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting chimeras
• Has a robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets
• Three investigational clinical-stage programs currently enrolling
• Committed to pioneering therapies created with the revolutionary PROTAC protein degradation platform