[Hiring] Scientific Narrative Lead @Praxis Precision Medicines

Role Description

This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Scientific Narrative Lead will own the strategic scientific story for one of Praxis’s lead development programs—ensuring that its science, data, differentiation, and potential value to patients are understood clearly and consistently from clinical development through regulatory submission, launch, and lifecycle management.

• Own the strategic scientific narrative for a lead Praxis program, building deep fluency in its science, data, development strategy, competitive context, and potential value to patients.
• Build and maintain a forward-looking narrative and communications roadmap that connects program strategy, emerging evidence, key milestones, regulatory interactions, publications, and launch preparation.
• Shape the scientific positioning and key messages within critical clinical and regulatory documents, including protocols, investigator brochures, clinical study reports, briefing documents, clinical overviews, and integrated summaries.
• Set narrative direction for US and global regulatory submissions, including INDs, NDAs, and MAAs, partnering closely with Regulatory Affairs, regulatory writing, Clinical Development, and program teams.
• Anticipate how new data, regulatory feedback, competitive developments, and program decisions should change—or reinforce—the scientific story.
• Serve as a connective thread across Clinical Development, Clinical Pharmacology, Nonclinical, Regulatory Affairs, Biostatistics, Data Management, Quality, CMC, Medical Affairs, and Commercial.
• Carry the scientific narrative forward as the program matures, including through launch, label expansion, new indications, and post-approval commitments.

Qualifications

• Bachelor’s degree in a scientific discipline required; an advanced scientific or clinical degree is preferred.
• 6+ years of experience in a biopharmaceutical sponsor, CRO, or consulting environment.
• Demonstrated ability to get deeply into complex scientific and clinical data, determine what matters, and synthesize it into a clear, compelling, and scientifically defensible story.
• Track record of shaping scientific positioning or messaging strategy for a drug development program.
• Strong understanding of drug development and the role of clinical, nonclinical, regulatory, statistical, CMC, and other evidence.
• Strong scientific writing capability, including experience developing or providing strategic direction for high-impact clinical and regulatory documents.

Requirements

• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.
• Comfort with screen work, basic hand coordination, and focus.
• Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Benefits

• Annualized Base Salary: $190,000 - $220,000 USD.
• 99% of the premium paid for medical, dental, and vision plans.
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans.
• 401(k) contributions matched dollar-for-dollar up to 6%.
• Long-term stock incentives and ESPP.
• Discretionary quarterly bonus.
• Flexible wellness benefit.
• Generous PTO, paid holidays, and company-wide shutdowns.

Company Description

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.

Our core Values of Trust, Ownership, Curiosity, and Results are foundational to every aspect of our business.

We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.