[Hiring] Head of In Silico Drug Toxicity/VP of Toxicology @Deep Origin

Role Description

We are seeking a Head of In Silico Drug Toxicity to own, define, and scale our computational toxicology platform end-to-end. This role operates as the general manager of the platform — effectively a CEO of the product — with full ownership across scientific vision, technical architecture, product strategy, and execution.

• Work cross-functionally with ML/AI teams, computational biologists, toxicologists, engineers, and commercial teams to build a category-defining platform for predictive toxicology.
• Requires both deep technical leadership and executive-level strategic thinking, with the ability to translate cutting-edge science into scalable, enterprise-ready systems.

Qualifications

• 15+ years in computational biology, toxicology, drug discovery, or related domain.
• Proven experience designing and deploying computational models for toxicity or biological systems.
• Demonstrated ability to develop novel modeling approaches beyond industry-standard methods.
• Deep hands-on experience designing and deploying computational toxicology models across mechanistic, statistical, and machine learning paradigms.
• Expertise in integrating ML/AI, systems biology, PK/PD modeling, and real-world data into cohesive predictive systems.
• Strong understanding of preclinical safety workflows.
• Familiarity with regulatory frameworks (FDA, EMA, ICH).
• Experience working with complex and proprietary pharma datasets.
• Strong communication and cross-functional leadership skills.

Requirements

• Experience leading large, interdisciplinary technical teams.
• Ability to operate as both a strategic leader and a technical decision-maker.
• Executive presence with senior pharma stakeholders.
• Experience building platforms, teams, or systems from zero to scale.
• Comfortable operating in ambiguity and defining direction.
• Strong bias toward action, ownership, and iteration.

Benefits

• Competitive compensation package with meaningful equity.
• Comprehensive health, dental, and vision coverage.
• Remote-friendly culture with optional onsite work.
• Annual team gatherings and company events.