[Hiring] Director, Clinical Systems & Data Management @Praxis Precision Medicines, Inc.

Role Description

This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

Praxis is hiring a Director, Clinical Systems & Data. You would lead the strategy, roadmap, and delivery of the clinical systems and data capabilities that support Praxis’s clinical development and study operations. This includes:

• Translating clinical priorities and study milestones into clear technology priorities.
• Making thoughtful investment and sequencing decisions.
• Driving delivery with urgency and accountability.

Within IT, you will own the clinical systems and data capability while partnering closely with Clinical Operations, Data & Analytics, Quality, Regulatory, and external technology providers. The role calls for:

• Creating clarity across functions.
• Establishing decision rights.
• Resolving competing priorities.
• Ensuring the systems and data supporting our clinical programs are reliable, scalable, secure, and fit for purpose.

You will provide leadership across clinical data engineering, data platform architecture, clinical systems delivery, and related validation activities. At the same time, you’ll stay close to the technology and the work, including:

• Challenging designs.
• Troubleshooting issues.
• Escalating when needed.
• Applying sound judgment to keep delivery moving.

You will also help shape how Praxis uses clinical technology and data to work better, moving the organization from fragmented or static workflows toward:

• Governed, reusable data products.
• Analytics and practical AI-enabled tools that help teams make better decisions and work more effectively.

Success will include building an operating model that:

• Scales with the organization.
• Strengthens inspection readiness and operational resilience.
• Reduces dependency on individual contributors.

Qualifications

• 10+ years of relevant experience across clinical systems, clinical data platforms, data engineering, technology delivery, or related disciplines, including leadership of complex cross-functional initiatives.
• Experience supporting pharmaceutical or biotechnology clinical development and delivering technology or data capabilities in a regulated environment.
• Strong understanding of the clinical technology ecosystem, including data integrations, cloud platforms, data architecture, analytics, and the operational needs of clinical teams.
• Experience with computerized systems validation, computer software assurance, GxP expectations, change control, data integrity, and inspection readiness.
• Ability to translate clinical and business priorities into practical roadmaps, investment decisions, delivery plans, and measurable outcomes, while effectively managing technology vendors and budgets.
• Technical fluency across data flows, APIs, integration patterns, cloud data platforms, and analytics tools, with the ability to challenge designs, identify dependencies, and guide delivery.
• Experience leading requirements definition, testing, user acceptance, change management, training, and transition to ongoing support.
• Demonstrated ability to lead technical teams and influence cross-functional stakeholders without relying solely on formal authority.
• A strong ownership mindset, with the ability to step into ambiguity, surface risks early, make decisions with appropriate urgency, and stay engaged through resolution.
• Comfort balancing speed with rigor, particularly in regulated environments.
• Clear, direct communication and the ability to adapt to different audiences while remaining technically engaged and contributing hands-on when needed.
• Alignment with Praxis values of Trust, Ownership, Curiosity, and Results.

Requirements

• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.
• You’ll need comfort with screen work, basic hand coordination, and focus.
• Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Benefits

• Annualized Base Salary: $205,000 — $229,000 USD.
• 99% of the premium paid for medical, dental, and vision plans.
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage.
• Dollar-for-dollar match up to 6% on eligible 401(k) contributions.
• Long-term stock incentives and ESPP.
• Discretionary quarterly bonus.
• Flexible wellness benefit.
• Generous PTO, paid holidays, and company-wide shutdowns.
• A collaborative team environment with smart, engaged, and inspiring colleagues.