[Hiring] Principal Software Engineer @Natera

Role Description

We're seeking a Principal Software Engineer to join Natera's R&D team. We build the cloud infrastructure, workflow platforms, and data platforms that R&D uses to do its science.

• Own the full architecture, implementation, and delivery of large projects across our platform.
• Partner with the team lead on roadmap and tough technical calls.
• Mentor mid-level engineers and help the team find the right solution for the problem.
• Work in a small team (4 engineers + lead) with broad scope, heavily AI-augmented.

Responsibilities

• Architecture & Delivery: Own the design, implementation, and delivery of major initiatives across our platform.
• Technical Leadership: Lead architecture and design reviews; influence technical decisions across the team.
• Mentorship: Mentor mid-level engineers through code review, design docs, and pairing.
• AI-Native Development: Build and improve our AI-coding tooling alongside the rest of the team.
• Cross-Functional Partnership: Work with bioinformaticians, scientists, and other R&D engineers to understand their needs.

Qualifications

• 10+ years of professional software engineering experience across a range of systems and problem types.
• Production experience with a major cloud platform (AWS preferred; GCP or Azure equivalent).
• Production experience with Kubernetes (or equivalent).
• Production experience with Terraform (or equivalent).
• Strong proficiency in at least one general-purpose language (Python, Go, Java, or similar).
• Experience shipping software to end users (internal or external).
• Experience leading an engineering team and mentoring junior engineers.
• Experience in fast-moving environments where results need to be delivered quickly.
• Familiarity with our tech stack: AWS, Kubernetes, Python, Go, Groovy, Terraform, Helm, Nextflow, WDL, Django, React.

Requirements

• Product-minded: Think in terms of business and user problems.
• Calibrated judgement: Know when to move fast and when to slow down.
• Actively excited about AI-native development.

Benefits

• Competitive salary and benefits.
• Annual performance incentive bonus.
• Long-term equity awards.
• Comprehensive health benefits (medical, dental, vision).
• 401(k) with company match.
• Generous paid time off and company holidays.
• Additional wellness and work-life benefits.