[Hiring] Global Trials Optimization Specialist / Project Manager I @Syneos Health Careers

Role Description

Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)

Are you energized by using data, strategic planning, and cross-functional collaboration to help clinical trials achieve enrollment success? We're seeking a Global Trials Optimization Specialist to support program feasibility, recruitment and retention strategy, and in-life trial optimization across global clinical studies within General Medicine, Dermatology, Rheumatology, Infectious Disease, and Vaccine programs.

In this role, you'll transform trial goals, country insights, enrollment analytics, and feasibility data into actionable strategies that drive study performance. Working closely with clinical trial teams, country stakeholders, vendors, legal partners, and analytics teams, you'll help identify enrollment opportunities, mitigate risks, and support effective patient and site engagement initiatives.

This is an outstanding opportunity for a clinical research professional who enjoys blending clinical operations, feasibility strategy, patient recruitment, stakeholder management, and data-driven decision-making to improve clinical trial outcomes on a global scale.

Job Responsibilities

• Program Feasibility and Trial Optimization
  • Gather data, benchmarks, and modeling inputs to support feasibility and trial optimization planning.
  • Support program review development, including content review and escalation of requirements as needed.
  • Plan timelines for validation, deliverable development, stakeholder alignment, presentation preparation, and country validation requests.
  • Support validation and Clinical Trials Allocation Committee activities, including scenario planning, risk table inputs, validation review, modeling updates, and final allocation requests.
  • Author the initial Global Trials Optimization Report and maintain subsequent report updates throughout the trial lifecycle.
  • Complete recruitment needs assessments and ensure trial-level GTO reports remain current and actionable.
• Recruitment and Retention Planning
  • Lead early recruitment and retention planning during feasibility, including inputs for project cost estimates.
  • Develop initial recruitment needs assessments and, where applicable, program-level recruitment budget estimates.
  • Submit vendor requests and prepare recruitment and retention plans.
  • Partner with legal on concept reviews, vendor proposal reviews, scope of work finalization, and material or tactic reviews.
  • Ensure recruitment and retention plans, including enrollment support materials, are implemented effectively.
  • Oversee enrollment support material development and tactic execution.
  • Provide required materials to the Metrics, Analytics & Performance team to support accurate Study Optimizer plan entry.
  • Request and manage appropriate system updates as trial needs evolve.
• In-Life Trial Management
  • Partner with study teams to identify enrollment challenges, assess risks, and recommend potential mitigations.
  • Manage routine enrollment support materials and vendor activities.
  • Monitor enrollment performance and prepare standard reporting.
  • Analyze performance trends and identify opportunities for enhanced support.
  • Coordinate enhanced enrollment support activities, which may include:
    • Rescue site and country activities
    • Internal recruitment and retention refresher meetings
    • External recruitment and retention booster meetings
    • Additional participant- or site-facing materials
    • Rescue vendor engagement
    • Advocacy engagement and community outreach

Qualifications

• Experience supporting clinical trials, feasibility assessments, recruitment planning, enrollment strategy, trial optimization, or related clinical operations activities.
• Strong analytical skills with the ability to collect, interpret, and apply data to support decision-making.
• Experience managing timelines, deliverables, stakeholder reviews, and cross-functional initiatives.
• Ability to collaborate effectively with study teams, vendors, legal partners, analytics groups, and operational stakeholders.
• Excellent written and verbal communication skills, including the ability to develop reports, recommendations, presentations, and strategic plans.
• Strong organizational skills and attention to detail in a fast-paced clinical research environment.
• Ability to manage multiple studies and competing priorities while maintaining quality and accuracy.

Requirements

• Experience supporting clinical trials within General Medicine, Dermatology, Rheumatology, Infectious Disease, or Vaccine therapeutic areas.
• Prior experience as a Clinical Research Coordinator, Site Coordinator, Clinical Trial Associate, or similar site-based research role.
• Experience with patient recruitment and retention vendors and enrollment support campaigns.
• Familiarity with patient engagement strategies and patient-centered trial approaches.
• Experience developing patient-facing or site-facing recruitment materials.
• Knowledge of enrollment forecasting, country validation processes, risk assessments, feasibility methodologies, or trial allocation strategies.
• Experience monitoring and analyzing enrollment performance metrics to drive operational improvements.

Benefits

• Company car or car allowance
• Health benefits to include Medical, Dental, and Vision
• Company match 401k
• Eligibility to participate in Employee Stock Purchase Plan
• Eligibility to earn commissions/bonus based on company and individual performance
• Flexible paid time off (PTO) and sick time