[Hiring] Director, Head of Product Management – AI-Enabled Precision Medicine @Natera

Role Description

We are seeking a Director / Head of Product Management to lead product strategy and execution for our AI-enabled therapeutics platform. This is a highly cross-functional leadership role at the center of science, engineering, clinical development, and commercial strategy.

• Define what we build, why it matters, and how it creates value for biopharma partners, clinicians, and ultimately patients.
• Own the product lifecycle end-to-end: from concept and validation through development, launch, and iteration.
• Blend of scientific fluency, product rigor, and commercial instinct.
• Work closely with R&D, AI, medical, business development, and marketing.

What You’ll Do

• Product Strategy & Vision:
  • Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings.
  • Identify high-value use cases across drug development.
  • Translate platform capabilities into clear product strategies aligned with business goals.
• Product Development & Execution:
  • Lead the end-to-end product lifecycle: concept → validation → build → launch → iteration.
  • Partner with R&D, data science, and engineering to define product requirements.
  • Drive prioritization decisions across competing opportunities.
• Customer & Market Insight:
  • Engage with biopharma partners, clinicians, and internal stakeholders.
  • Synthesize customer insights into product requirements and roadmap decisions.
  • Continuously assess market trends, competitive landscape, and emerging technologies.
• Cross-Functional Leadership:
  • Serve as the central hub across Product, R&D, Clinical, BD, and Marketing.
  • Align stakeholders around a unified product strategy and execution plan.
  • Drive decision-making in a matrixed, fast-moving environment.
• Commercialization & Launch:
  • Partner with commercial and BD teams to define product positioning, packaging, and pricing.
  • Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments.
  • Ensure successful product launches with clear value propositions and supporting evidence.
• Data, Evidence & Validation:
  • Define requirements for product validation, including analytical, clinical, and real-world evidence.
  • Ensure products meet scientific, regulatory, and commercial expectations.
  • Partner with clinical and regulatory teams to align product strategy with approval pathways.
• Team Building & Leadership:
  • Build and mentor a high-performing product management function.
  • Establish product processes, operating cadence, and best practices.
  • Foster a culture of ownership, speed, and scientific rigor.

Qualifications

• Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.
• 8–12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology.
• Proven track record of building and launching complex, data-driven products.
• Strong understanding of drug development workflows and/or clinical diagnostics.
• Experience working with AI/ML-driven products or data platforms is highly preferred.
• Exceptional ability to translate complex science into clear product decisions and strategies.
• Demonstrated success leading cross-functional teams in ambiguous environments.
• Strong commercial acumen, including product-market fit, pricing, and partnership models.

Benefits

• Annual performance incentive bonus
• Long-term equity awards
• Comprehensive health benefits (medical, dental, vision)
• 401(k) with company match
• Generous paid time off and company holidays
• Additional wellness and work-life benefits

Compensation Range

$184,600 — $230,700 USD