[Hiring] Head of Medical Safety Assessment @argenx

Role Description

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. The Head of Medical Safety Assessment serves as a senior medical leader for Global Patient Safety with direct accountability for medical safety assessment across development assets and geographies. The role sets the cross-portfolio medical safety assessment strategy and ensures consistent, high-quality benefit–risk evaluation, safety decision-making, and safety communications throughout the product lifecycle.

The role provides functional and people leadership to a combined global team of Safety Physicians and Safety Scientists and is accountable for excellence in the core delivery of patient safety, including:

• Signal detection and management
• Risk management
• Aggregate safety reporting

The Head of Medical Safety Assessment acts as a primary medical point of escalation for complex or non-routine safety issues and provides expert guidance to asset, development, and medical teams.

This role will interface with the following:

• Internal: Global Patient, Global Regulatory Sciences, Clinical Development, Biostatistics / Quantitative Sciences, Medical Affairs, HEOR, RWE, Quality, Legal, Commercial (as appropriate).
• External: Health Authorities, Independent Data Monitoring Committees, Key Opinion Leaders and External Experts, strategic partners, vendors, and CROs.

Qualifications

• MD or equivalent medical degree required.
• Minimum of 15 years of pharmaceutical or biotechnology industry experience.
• At least 10 years of leadership experience in pharmacovigilance and medical safety.
• Demonstrated experience overseeing leading innovation initiatives within a patient safety organization.
• Experience with signal management, aggregate safety reports, and risk management activities.
• Proven track record leading global, multidisciplinary medical safety teams.
• Experience interacting with Health Authorities on complex and strategic safety topics.
• Experience implementing novel technologies and leveraging emerging data sources relevant to patient safety is strongly preferred.

Requirements

• Senior medical leadership, committed to innovation, and strategic influence aligned with the argenx ways of working.
• Deep expertise in signal management, benefit–risk assessment, risk management, and aggregate reporting.
• Strong knowledge of global pharmacovigilance regulations and safety governance.
• Enterprise mindset with the ability to balance scientific rigor, patient-first thinking, and business impact.
• Demonstrated ability to empower teams, foster accountability, and develop senior experts.
• Strong communication skills with the ability to influence across functions and leadership levels.
• Scientific curiosity, analytical rigor, and comfort navigating ambiguity and complexity.
• Interest in and aptitude for applying advanced technologies, data, and analytics to medical safety.
• Proficiency with standard business tools (e.g., Microsoft Office).
• Fluency in written and spoken English.

Benefits

• Annual base salary hiring range: $292,000.00 - $401,500.00 USD.
• Participation in short-term and long-term incentive programs.
• Comprehensive benefits package, including retirement savings plans and health benefits.