[Hiring] Executive Medical Director, Clinical Development @Syndax Pharmaceuticals

Role Description

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. The Executive Medical Director, Clinical Development will report to the Global Head of Development and is responsible for the creation and execution of clinical development plans within cross-functional project teams.

• Oversee several preclinical and clinical stage assets.
• Provide clinical input into business development opportunities.
• Work closely with key internal and external stakeholders.
• Provide input into global regulatory strategy development.
• Participate in the preparation of submission documents and responses to regulatory agency queries.
• Be a strategic leader providing a strong, clear voice for the clinical program.

Key Responsibilities

• Develop and implement clinical development plans and study protocols in conjunction with a multidisciplinary Development Team.
• Represent clinical development with senior internal and external stakeholders.
• Provide input and clinical assessment for business development opportunities.
• Ensure robust clinical input into Target Product Profiles (TPPs).
• Provide robust clinical input into global regulatory strategy and co-lead interactions with global Health Authorities.
• Support the identification and selection of clinical investigators for clinical trials.
• Conduct medical assessment and disposition of adverse events in conjunction with Drug Safety physician.
• Oversee the clinical trials program in accordance with NBI SOPs, Good Clinical Practice, and applicable regulations.
• Analyze, interpret, and present results of clinical studies to internal and external audiences as directed by Senior Management.
• Identify resource requirements and assist in budget planning and personnel forecasting for clinical research programs.
• Assist in the recruitment, training, and development of clinical teams.
• Identify and select clinical consultants as needed.
• Responsible for the scientific writing and review of clinical study reports and related regulatory documents.
• Provide periodic status updates and effectively communicate with the Senior Management Team.
• Collaborate with translational medicine for the development of clinical biomarker strategies.
• Work with Medical Affairs and external opinion leaders to secure new collaborators.
• Present trial results and shape Investigator-Sponsored Trial (IST) strategy.
• Other duties as assigned.

Qualifications

• MD or MD/PhD with 5-10 years’ experience in clinical research, preferably in an industry setting.
• Sub-specialty training or board certification in hematology, oncology, or related field preferred.
• Experience in early development and with designing first-in-human studies is a plus.
• Track record of building Clinical Development Plans (CDPs) with a cross-functional team.
• Strong ability to integrate biological knowledge into clinical development strategy.
• A creative problem solver with the proven ability to work independently and collaboratively.
• Recognized as an internal medical leader with extensive technical expertise.
• Able to manage interactions with external CROs, consultants, and other contract organizations.
• Ability to evaluate key business/scientific challenges and complete complex initiatives.
• Able to work independently and prioritize multiple tasks and goals.
• Excellent interpersonal skills and strong written and verbal communication skills.
• Experience with working in an alliance would be a plus.

Location

Syndax’s corporate office is in New York, NY.

Benefits

• Total compensation and rewards package among the most competitive in the industry.
• Base pay determined within a range based on several factors including market data, experience, qualifications, and internal equity.
• Overall package includes an equity offering, annual target bonuses, and an outstanding benefits program.
• Anticipated annualized salary range for this role is $380,000 - $400,000.

Company Description

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company’s pipeline include:

• A menin inhibitor for R/R acute leukemia.
• A monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease.

For more information, please visit www.syndax.com or follow the Company on X and LinkedIn.

Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.