[Hiring] Director, US Medical Affairs @Revolution Medicines

Role Description

The Director, US Medical Affairs - PDAC will support the development and execution of the US Medical Affairs strategy and tactical plan for pancreatic ductal adenocarcinoma (PDAC). The role will serve as a US medical and scientific partner for cross-functional teams and help translate the evolving PDAC treatment landscape, external expert perspectives, and field insights into focused medical priorities and activities.

• Contributes to the development and execution of the US Medical Affairs strategy and annual medical plan for PDAC, including launch readiness, launch execution, and lifecycle planning.
• Translates US-specific evidence gaps, treatment patterns, stakeholder needs, and field insights into clear medical objectives and executable tactics.
• Leads or supports scientific engagement with US external experts through advisory boards, investigator interactions, congress activities, and peer-to-peer scientific exchange.
• Partners with US Field Medical to develop scientific priorities, insight-generation plans, training, and resources that support high-quality scientific exchange.
• Synthesizes insights from external experts, field teams, advisory boards, and other medical activities and communicates implications to internal stakeholders.
• Serves as the PDAC medical content expert on US cross-functional teams and provides scientifically balanced medical input into strategic discussions and decisions.
• Partners with HEOR/RWE, Clinical Development, and Biomarker/Companion Diagnostics teams on evidence-generation priorities addressing US clinical practice, patient identification, biomarker testing, treatment sequencing, safety management, and patient outcomes.
• Coordinates gap assessments and contributes to publication, congress, medical communications, and evidence-generation plans aligned with the US medical strategy.
• Supports the development and review of scientific materials, medical education content, medical information response documents, abstracts, manuscripts, and data-disclosure materials.
• Provides medical leadership for US congress planning, scientific symposia, advisory boards, and other medical activities, ensuring consistency, scientific accuracy, and compliance.
• Partners with Patient Advocacy and Grants teams to incorporate the patient and caregiver perspective and help identify appropriate independent medical education priorities.
• Collaborates with Safety and Clinical teams to support education and scientific exchange related to adverse-event recognition and management in PDAC.
• Ensures all activities are conducted in accordance with applicable legal, regulatory, and compliance requirements.

Qualifications

• Advanced clinical or scientific degree such as PharmD, PhD, MD, DO, or equivalent.
• 10+ years of relevant experience in Medical Affairs within biotechnology or the pharmaceutical industry and/or prior clinical oncology practice.
• Strong scientific background in oncology, with meaningful experience in gastrointestinal cancers and a strong preference for direct PDAC experience.
• Demonstrated ability to analyze, synthesize, and communicate complex clinical and scientific information to internal and external audiences.
• Hands-on experience across core Medical Affairs activities, such as medical strategy, field medical partnership, medical communications, medical information, evidence generation, publications, congress planning, advisory boards, and internal training.
• Experience working effectively with cross-functional partners, including Clinical Development, HEOR/RWE, Biomarkers/Diagnostics, Commercial, Market Access, Regulatory, Safety, Legal, and Compliance.
• Excellent written, verbal, and presentation skills, with the ability to communicate a clear scientific point of view while maintaining appropriate medical balance.
• Ability to manage multiple priorities and stakeholders in a dynamic, evolving environment.
• Ability to travel for internal meetings, external expert engagements, and medical congresses, as required.

Preferred Skills

• Established relationships with US PDAC experts, investigators, advocacy organizations, and multidisciplinary care stakeholders.
• Experience supporting oncology product launch readiness, launch execution, or post-launch medical strategy in the United States.
• Experience in precision oncology, RAS biology, biomarker testing, companion diagnostics, or targeted therapy development.
• Understanding of the US PDAC care pathway, including community and academic treatment settings, patient referral patterns, molecular testing, treatment sequencing, and key evidence gaps.
• Experience supporting clinical-trial strategy or execution, including protocol review, site and investigator engagement, enrollment support, and interpretation of clinical data.

Benefits

• Competitive cash compensation.
• Robust equity awards.
• Strong benefits.
• Significant learning and development opportunities.

Base Pay Salary Range

$201,000 — $251,000 USD