[Hiring] Director, Clinical Genomics Operations & Variant Science @Labcorp

Role Description

Labcorp is seeking a US remote-based Director of Clinical Genomics Operations & Variant Science to join its Invitae Genetics division!

• Provide strategic, technical, and operational leadership for clinical interpretation and reporting across WGS, WES, targeted NGS panels, and chromosomal microarray (CMA).
• Serve as subject matter expert in genomic testing workflows, interpretation frameworks, and clinical reporting standards — ensuring scientific rigor, clinical relevance, and regulatory compliance.
• Oversee day-to-day operational performance including production scheduling, capacity planning, process health monitoring, and escalation of operational incidents.
• Establish, optimize, and scale end-to-end workflows for clinical interpretation and reporting using continuous improvement methodologies.
• Define, implement, and monitor key operational metrics to assess performance, identify risk, and communicate trends to senior leadership.
• Ensure delivery of high-quality clinical reports meeting established turnaround time, accuracy, and quality benchmarks.
• Lead root-cause analysis and implementation of corrective and preventive actions for complex production issues.
• Develop and execute operational strategies aligned with broader organizational OKRs.
• Mentor and coach scientists, genetic counselors, and operational partners — fostering a culture of continuous learning and scientific excellence.
• Collaborate cross-functionally with Laboratory, Bioinformatics, Product, Quality, Regulatory, IT, and Clinical Development to support launch of new assays, tools, and initiatives.
• Act as an individual-contributor Director with expectation of transitioning to formal people management within ~6 months.

Qualifications

• PhD in Biological Sciences, Molecular Genetics, or Human Genetics with 5 years or more of related work experience; OR Master's degree in Genetic Counseling, Biological Sciences, Molecular Genetics, or Human Genetics with 6 years or more of related work experience; OR Bachelor's degree in Genetics, Biological Sciences, Molecular Genetics, or Human Genetics with 7 years or more of related work experience.
• 3 years or more of demonstrated expertise in variant interpretation, curation, and clinical reporting for NGS-based assays, including WGS and WES and/or targeted panels.
• 3 years or more of experience driving operational efficiency and scaling production workflows supporting clinical interpretation and/or reporting.
• 3 years or more of experience managing or influencing complex initiatives with measurable outcomes in a high-throughput setting.
• 5 years or more of experience in operational leadership, including managing a team, workflow optimization, capacity planning, performance metrics, and cross-functional execution.

Requirements

• 5 years or more of Director-level experience within a CLIA-certified diagnostic laboratory or similarly regulated clinical setting.
• 3 years or more of experience developing, launching, or scaling clinical genomic assays or interpretation programs.
• 2 years or more of experience with rapid or NICU whole genome sequencing (NICU WGS) and high-acuity clinical workflows.
• 2 years or more of familiarity with copy number variant (CNV) detection and interpretation across CMA and NGS-based platforms.
• Lean Six Sigma (Green Belt or higher) certification or equivalent continuous improvement experience.
• 3 years or more of experience scaling high-throughput clinical interpretation/reporting operations.

Benefits

• Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan.
• Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan.
• Employees who are regularly scheduled to work a 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO.