[Hiring] 2027 Summer Intern - Computational Science @Roche

Role Description

2027 Summer Intern - Computational Science

We advance science so that we all have more time with the people we love.

The XOOS Algorithm Development team leads secondary analysis algorithm development for Sequencing by Expansion (SBX) data on the AXELIOS platform. We bridge rapid R&D prototyping with production-grade bioinformatics tools, driving multi-omics whole genome and targeted sequencing applications across oncology, genetic disease, and infectious disease.

This internship position is fully remote.

The Opportunity:

• Algorithm Development
• Benchmarking
• Software development
• Presenting results to stakeholders

Program Highlights:

• Intensive 12-weeks, full-time (40 hours per week) paid internship
• Program start dates are in May/June (Summer)
• A stipend, based on location, will be provided to help alleviate costs associated with the internship
• Ownership of challenging and impactful business-critical projects
• Work with some of the most talented people in the biotechnology industry

Qualifications

• Must be pursuing a PhD (enrolled student)
• Required Majors: Bioinformatics, Computer Science, Computational Biology

Requirements

• Advanced experience developing bioinformatics algorithms for secondary analysis of sequencing data
• Demonstrated expertise in detecting genetic variation in challenging genomic contexts, including repeat regions, paralogs, pseudogenes, and highly homologous loci
• Strong understanding of haplotype phasing, read alignment, local or de novo assembly, scaffolding, and pangenome methods
• Experience developing tools for one or more of the following:
  • Repeat expansion or repeat-genotype analysis
  • Paralog- or pseudogene-aware variant calling
  • Long-read or highly accurate sequencing analysis
  • Haplotype reconstruction and phasing
  • De novo or targeted assembly
  • Graph genomes or pangenome analysis
• Strong programming skills in Python and/or C++, with experience building reproducible, tested software
• Experience evaluating algorithms with representative datasets and quantitative performance metrics
• Currently enrolled in or recently graduated from a degree program in bioinformatics, computational biology, computer science, statistics, mathematics, genomics, or a related field

Benefits

• Relocation benefits are not available for this job posting
• The expected salary range for this position based on the primary location of California is $47.00-$52.00 per hour
• Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law
• This position also qualifies for paid holiday time off benefits