[Hiring] Vice President, Laboratory Software Engineering @Natera

Role Description

The Vice President of Laboratory Software Engineering is an enterprise executive role responsible for the strategy, modernization, and delivery of informatics platforms that power sample accessioning, order and sample tracking, and end-to-end workflow orchestration across both wet and dry laboratories.

This role leads an organization of approximately 200 people and supports multiple business units, including:

• Oncology Minimal Residual Disease (MRD)
• Oncology Comprehensive Genomic Profiling (CGP)
• Early Cancer Detection (ECD)
• Women’s Health (WH)
• Organ Health (OH)

Operating in a CLIA- and CAP-certified clinical laboratory environment with FDA-regulated diagnostics, the VP will lead the transformation of a fully homegrown informatics ecosystem. This leader is accountable for defining enterprise platform strategy, driving large-scale modernization, and making critical build-vs-buy decisions to ensure scalability, reliability, regulatory compliance, and operational excellence.

In the first 90 days, the VP is expected to:

• Build strong relationships with laboratory, product, engineering, quality, and regulatory stakeholders.
• Develop a deep understanding of existing informatics platforms and laboratory workflows.
• Assess organizational strengths and gaps.
• Establish credibility with laboratory users through direct engagement, including onsite interaction.
• Identify near-term risks and opportunities while defining clear principles for platform modernization.

Within the first year, the VP is expected to:

• Define and begin executing a multi-year enterprise informatics roadmap.
• Make key architectural and build-vs-buy decisions.
• Align the organization around standardized platforms.
• Demonstrate measurable improvements in scalability, reliability, and operational efficiency.

Qualifications

• 15+ years of progressive experience in laboratory informatics, enterprise software platforms, or large-scale systems supporting regulated, mission-critical environments.
• Demonstrated success leading large, complex organizations (100+ people), preferably at the VP or equivalent senior leadership level.
• Deep understanding of laboratory workflows, including sample accessioning, order and sample tracking, and wet-lab and dry-lab orchestration.
• Proven experience modernizing legacy or homegrown platforms, including leading major architectural transformations and build-vs-buy decisions.
• Strong executive presence with the ability to influence across functions and communicate effectively with technical and non-technical stakeholders.

Requirements

• Experience supporting CLIA- and CAP-certified clinical laboratories.
• Familiarity with FDA-regulated diagnostics, LDTs, and regulatory submissions.
• Hands-on experience with CSV, audit readiness, and regulated system lifecycle management.
• Background in genomics, oncology diagnostics, or other high-throughput laboratory environments.

Benefits

• Competitive compensation package, including base salary, performance-based incentives, and equity participation.
• Comprehensive medical, dental, vision, life, and disability plans for eligible employees and their dependents.
• Free testing for employees and their immediate families, in addition to fertility care benefits.
• Pregnancy and baby bonding leave, 401k benefits, commuter benefits, and more.
• A generous employee referral program.

Company Description

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly, being part of a company that is changing the landscape of genetic disease management.