[Hiring] Director of Commercial IT Systems @Praxis Precision Medicines

Role Description

This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

Praxis is building the commercial capabilities needed to bring new therapies to patients. We’re looking for a Director of Commercial Systems to own the strategy, roadmap, and business performance of the technology supporting commercial launch and growth.

Reporting to the Vice President of Information Technology, you will lead Commercial Systems within IT. Partner with Sales, Marketing, Commercial Operations, and Market Access to translate business priorities into a coordinated roadmap, lead delivery, and ensure reliable systems and trusted data.

You will directly manage enterprise applications strategy and development and partner with IT peers, Data & Analytics, and commercial business owners. This role combines strategic leadership with accountability for delivery, reliability, launch readiness, and adoption.

Primary Responsibilities

• Own the commercial systems strategy and roadmap.
• Establish business ownership and decision-making for commercial systems.
• Lead commercial systems delivery from planning through adoption.
• Own business requirements and service expectations for CRM and its connections to commercial data.
• Partner with Data & Analytics to define the commercial data and reporting capabilities needed for launch and growth.
• Own vendor performance, service expectations, and the commercial systems investment plan.
• Lead launch readiness, user acceptance, training, and change management with business owners.
• Partner with IT, Security, Privacy, Legal, and Quality to incorporate access controls and compliance requirements.

Qualifications

• 10+ years of relevant experience in commercial technology, enterprise applications, or related roles.
• Experience supporting pharmaceutical or biotechnology commercial operations.
• Strong understanding of CRM, field workflows, commercial data, and digital engagement.
• Ability to translate commercial strategy into a practical roadmap and business cases.
• Technical fluency in data flows, APIs, integration patterns, and cloud data platforms.
• Experience leading requirements definition, user acceptance testing, and change management.
• Sound judgment in handling sensitive commercial and healthcare data.
• Clear communication and effective influence across functions.

Requirements

• Launch readiness: Critical commercial workflows are tested and ready when needed.
• Clear ownership: Decisions, priorities, and accountability are explicit.
• Business impact: Systems are adopted, data is trusted, and investments deliver measurable improvements.
• Practical leadership and caring candor: Simplify complexity and build strong delivery partnerships.

Benefits

• 99% of the premium paid for medical, dental, and vision plans.
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans.
• 401(k) match dollar-for-dollar up to 6% on eligible contributions.
• Long-term stock incentives and ESPP.
• Discretionary quarterly bonus and flexible wellness benefit.
• Generous PTO, paid holidays, and company-wide shutdowns.

Company Description

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.

Our core Values of Trust, Ownership, Curiosity, and Results are foundational to every aspect of our business.

At Praxis, we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion.